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  • A new drug approved for weight-loss through the U.S. Food and Drug Administration had good results in clinical trials, however it isn't a panacea for weight loss. It must be found in combination with a low-calorie diet and routine workouts in order to be effective.

    Using two separate drugs to shed pounds can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the people who go through it one should err along the side of caution and permit the FDA do its job and demand some study be done so the public is aware of the side effects and hazards of the medications before we bring them. Keep in mind that drug companies come in business to make money and that they would say anything to keep people on their own medications.

    Researchers found that participants using this drug for a year, lost weight within a month and have kept the load off throughout the 56 weeks from the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs that are made up of several active ingredient, that might make them more effective and safer.

    Combo-pilling will be the newest fad or in addition to this the newest into the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular will be the fact that as of right now there are no long term prescription weight loss supplements that have been approved by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be approved by the FDA.

    Seizures are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug may also raise blood pressure levels and heartrate, and must not be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise hypertension and heart rate and must 't be used in patients with uncontrolled high hypertension, in addition to by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients having a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients towards the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.

    "This will be the first drug I'm alert to that targets the appetite and reward centres within the brain," he said.